Administration of oxazolidinone and pyrolidinone compounds for the treatment of inflammation

US5783591A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Walter Klose · Berlin, DE
• Gerald Kirsch · Berlin, DE
• Andreas Huth · Berlin, DE
• Wolfgang Froehlich · Berlin, DE
• Henry Laurent

Key dates

• Filing date: Nov 17, 1994
• Grant date: Jul 21, 1998
• Expiry date: Nov 17, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D413/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pharmaceutical preparations for the local treatment of inflammations are claimed herein, characterized in that they contain as the active ingredient one or two compounds of general Formula I ##STR1## wherein X is an oxygen atom or a methylene group, PA1 R.sub.1 and R.sub.2 represent a hydrogen atom or a hydrocarbon residue of maximally eight carbon atoms, optionally interrupted by an oxygen atom, PA1 R.sub.3 is a hydrogen atom or a hydrocarbon residue of maximally eight carbon atoms, optionally substituted by an oxo group, and PA1 R.sub.4 is a hydrogen atom or an alkyl group of maximally four carbon atoms.