Inhibitors of squalene synthetase and protein farnesyltransferase
US5783593A · kind A · utility
10Cited by
17References
26Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 29, 1996 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Apr 29, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C2603/74
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention provides a compound of the formula ##STR1## which inhibit squalene synthetase and cholesterol biosynthesis and are useful in the treatment of e.g., hyperlipidaemia, atherosclerosis, or fungal infections, processes for the preparation of the compounds of the invention, intermediates useful in these processes, and pharmaceutical compositions containing the compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.