Patent · US Expired

Methods for synthesizing sulfated disaccharide inhibitors of selectins

US5783693A · kind A · utility

11Cited by

2References

6Claims

0Family size

Assignee

The Regents of the University of California · US

Inventors

Carolyn R. Bertozzi · Berkeley, US
Steven D. Rosen · San Francisco, US

Key dates

Filing date	Aug 23, 1995
Grant date	Jul 21, 1998
Priority date	—
Expiry date	Aug 23, 2015

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H11/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Sulfated disaccharides characterized by the ability to inhibit the binding of selectin to its physiologically-relevant ligand are disclosed. Included are efficient and inexpensive methods for producing the sulfated disaccharides, and methods for their therapeutic use and in in vivo and in vitro assays.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.