Spectral bio-imaging methods for biological research, medical diagnostics and therapy
US5784162A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 12, 1995 |
| Grant date | Jul 21, 1998 |
| Priority date | — |
| Expiry date | Dec 12, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2021/6423
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
According to the present invention there are provided spectral imaging methods for biological research, medical diagnostics and therapy comprising the steps of (a) preparing a sample to be spectrally imaged; (b) viewing the sample through an optical device, the optical device being optically connected to an imaging spectrometer, the optical device and the imaging spectrometer obtaining a spectrum of each pixel of the sample by: (i) collecting incident light simultaneously from all pixels of the sample using collimating optics; (ii) passing the incident collimated light through an interferometer system having a number of elements, to form an exiting light beam; (iii) passing the exiting light beam through a focusing optical system which focuses the exiting light beam on a detector having a two-dimensional array of detector elements, so that at each instant each of the detector elements is the image of one pixel of the sample, so that the real image of the sample is stationary on the plane of the detector array, and so that each of the detector elements produces a signal which is a particular linear combination of light intensity emitted by the pixel at different wavelengths, wherein…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.