Metal chelate forming peptides and use thereof represented by three amino acid sequences
US5785948A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 12, 1997 |
| Grant date | Jul 28, 1998 |
| Priority date | — |
| Expiry date | Mar 12, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides, inter alia, metal radionuclide-labelled reagent comprising a metal radionuclide coordinated with a metal chelate forming peptide having an amino acid sequence of three amino acid residues represented by: X1-X2-Cys, wherein X1 represents an Asp residue, a Tyr residue or a Lys residue; X2 represents an amino acid residue other than a Cys residue and a Pro residue, provided that X2 does not represent a Gly residue when X1 represents an Asp residue; wherein functional groups at the N-terminus, C-terminus and side chain may be optionally substituted with protecting groups; and wherein each of the amino acid residues may be either D-form or L-form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.