Patent · US Expired

Human geranylgeranyl pyrophosphate synthethase

US5786193A · kind A · utility

13Cited by
6References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 1995
Grant dateJul 28, 1998
Priority date
Expiry dateJun 6, 2015

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12N2799/026
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A human geranylgeranyl pyrophosphate synthetase polypeptide and DNA (RNA) encoding such polypeptide and procedure for producing such polypeptide by recombinant techniques is disclosed. Also disclosed are methods for utilizing such polypeptide for controlling morphology of cells. Antagonist against such polypeptides and their use as a therapeutic to treat cancer is also disclosed. Diagnostic assays are also disclosed which detect the presence of a mutated form of hGGPS and over-expression of the hGGPS protein.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.