Patent · US Expired

Streptogramin derivatives, their preparation and pharmaceutical compositions which contain them

US5786449A · kind A · utility

1Cited by
1References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 31, 1997
Grant dateJul 28, 1998
Priority date
Expiry dateJan 31, 2017

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61K38/00
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Streptogramine derivatives of general formula (I) below, wherein the radical R.sub.1 is a methyl or ethyl radical, the radical R.sub.2 is a bromine or chlorine atom, or is an alkenyl radical with 3 to 5 carbon atoms when R.sub.3 and R.sub.4 are methyl, and one of R.sub.3 and R.sub.4 is a hydrogen atom or a methyl radical and the other is a methyl radical are disclosed. The streptogramine derivatives of general formula (I) have particularly useful antibacterial properties, and may be used in combination with a pristinamycin II derivative. ##STR1##

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.