Process for preparation of 1,3-propanediol via hydrogenation of 3-hydroxypropanal
US5786524A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | May 30, 1996 |
| Grant date | Jul 28, 1998 |
| Priority date | — |
| Expiry date | May 30, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C45/58
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
1,3-propanediol is prepared from 3-hydroxypropanal in a process comprising the steps of: PA1 (a) contacting, at a temperature within the range of about 50.degree. to about 100.degree. C. and a pressure within the range of about 500 to about 5000 psig, ethylene oxide with carbon monoxide and hydrogen in an essentially non-water-miscible solvent in the presence of an effective amount of a non-phosphine-ligated cobalt or rhodium catalyst and an effective amount of a catalyst promoter under reaction conditions effective to produce an intermediate product mixture comprising less than 15 wt % 3-hydroxypropanal; PA1 (b) adding an aqueous liquid to said intermediate product mixture and extracting into said aqueous liquid a major portion of the 3-hydroxypropanal at a temperature less than about 100.degree. C. so as to provide an aqueous phase comprising 3-hydroxypropanal in a concentration of at least about 20 wt %, and an organic phase comprising at least a portion of the cobalt or rhodium catalyst or a cobalt- or rhodium-containing derivative thereof; PA1 (c) separating the aqueous phase from the organic phase; PA1 (d) diluting the aqueous phase comprising 3-hydroxy-propanal with an aqueo…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.