Vaccine composition for eliciting an immune response against N-glycolylated gangliosides and its use for cancer treatment
US5788985A · kind A · utility
5Cited by
2References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 29, 1994 |
| Grant date | Aug 4, 1998 |
| Priority date | — |
| Expiry date | Dec 29, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/828
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides novel uses for n-glycolylated gangliosides, or derivatives and/or oligosaccharides thereof. The invention further provides methods of obtaining such gangliosides, as well as vaccine compositions comprising said gangliosides. The gangliosides may be coupled to carriers and may be accompanied by adjuvants. The vaccine compositions can be used in the treatment of breast cancers, whereby the gangliosides are used to elicit an immune response to corresponding gangliosides on breast tumour cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.