Sterile aqueous parenteral formulations of cis-diammine dichloro platinum
US5789000A · kind A · utility
26Cited by
0References
3Claims
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Assignee
Inventors
Key dates
| Filing date | Nov 14, 1994 |
| Grant date | Aug 4, 1998 |
| Priority date | — |
| Expiry date | Nov 14, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention describes a novel formulation containing both cis-diammine dichloro platinum and a water soluble disulfide, 2,2'-dithio-bis-ethane sulfonate in the same solution, wherein the presence of the disulfide and the parenteral administration of the formulation reduces the risk of cisplatin induced nephrotoxicity when treating human patients with cancer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.