Indeno1,2-E!pyrazine-4-ones, their preparation and the medicaments containing them
US5789406A · kind A · utility
1Cited by
6References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 27, 1996 |
| Grant date | Aug 4, 1998 |
| Priority date | — |
| Expiry date | Sep 27, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P39/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The compounds of formula (I) ##STR1## wherein R, R.sub.1 and R.sub.2 are defined in the disclosure, and salts thereof. The compounds of formula (I) are non-competitive N-methyl-D-asparate (NMDA) receptor antagonists, particularly NMDA receptor glycine modulation site ligands, and are alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor antagonists, this receptor is also known as the quisqualate receptor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.