Treatment of urinary incontinence with nitric oxide synthase substrates and/or nitric oxide donors alone or in combination with estrogen or progesterone and/or other agents
US5789442A · kind A · utility
90Cited by
2References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 18, 1996 |
| Grant date | Aug 4, 1998 |
| Priority date | — |
| Expiry date | Jan 18, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P13/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides a method for the treatment and prevention of urinary incontinence in mammals, e.g., human males and females, especially nonpregnant female mammals, by administering a nitric oxide synthase substrate and/or nitric oxide donor, alone or in combination with an estrogenic agent and/or a progestational substance, with or without supplementation with an alpha-adrenergic agonist, beta-adrenergic receptor blocking agent, cholinergic-receptor blocking compound or a cholinergic-receptor-stimulating drug, as well as pharmaceutical compositions useful in practicing the methods of this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.