Method for preparing streptogramins
US5789537A · kind A · utility
1Cited by
2References
6Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 16, 1997 |
| Grant date | Aug 4, 1998 |
| Priority date | — |
| Expiry date | Oct 16, 2017 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for preparing streptogramins of the formula (I): ##STR1## wherein R.sub.1 is methyl or ethyl, R.sub.2 is H and X and Y together form an oxo radical, or R.sub.1 is ethyl, R.sub.2 and X are H and Y is H or OH, or else R.sub.1 is ethyl, R.sub.2 is OH and X and Y together form an oxo radical, by demethylation of a synergistin derivative of the formula (II): ##STR2## wherein R.sub.1, R.sub.2, X and Y are as defined above, by means of a treatment with a periodate in an acetic medium, followed by a treatment in an aqueous medium.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.