Patent · US Expired

Methylphosphonate dimer synthesis

US5789576A · kind A · utility

18Cited by
1References
30Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 9, 1994
Grant dateAug 4, 1998
Priority date
Expiry dateDec 9, 2014

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07H19/04
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Processes for the stereospecific synthesis of 2',2"-bis(deoxy)di-nucleosides and for the stereoselective synthesis of 2',2"-bis(substituted) dinucleosides are provided. Also provided are activated 2'-substituted-nucleoside alkylphosphonate active esters useful in the synthesis of these dinucleosides.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.