Synthetic techniques and intermediates for polyhydroxy, dienyl lactones and mimics thereof

US5789605A · kind A · utility

Assignee

• The Trustees of the University of Pennsylvania · US

Inventors

• Amos B. Smith, III · Yeadon, US
• Yuping Qiu · Princeton Junction, US
• Michael Kaufman · Ypsilanti, US
• Hirokaza Arimoto · Drexel Hill, US
• David Jones · Milford, US
• Kaoru Kobayashi · Osaka, JP

Key dates

• Filing date: Dec 3, 1996
• Grant date: Aug 4, 1998
• Expiry date: Dec 3, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F7/1892
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Synthetic methods for lactone-containing compounds such as the discodermolides are provided, as are compounds which mimic the chemical and/or biological activity thereof, and methods and intermediates useful in their preparation.