Non-insulin-dependent diabetic rat
US5789652A · kind A · utility
1Cited by
0References
4Claims
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Assignee
Inventors
Key dates
| Filing date | Dec 6, 1995 |
| Grant date | Aug 4, 1998 |
| Priority date | — |
| Expiry date | Dec 6, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K67/027
- WIPO fieldOther special machines
- WIPO sectorMechanical engineering
Abstract
This invention relates to a non-insulin-dependent diabetic disease model rat derived and established from Long-Evans rats, more particularly, a non-insulin-dependent diabetic rat having specific biochemical gene markers in organs, plasma and red blood cells, with erythrocytes and B lymphocytes having specific major histocompatibility antigen markers, showing increases in plasma glucose and insulin levels on oral glucose loading and increases in urinary protein level with aging, with diabetic nephropathy manifested by nodular and diffuse lesions of the glomerulus of the kidney accompanying in individuals with glycosuria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.