Assay using oxidative chromogenic reagent
US5792619A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jan 30, 1997 |
| Grant date | Aug 11, 1998 |
| Priority date | — |
| Expiry date | Jan 30, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2326/96
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
An oxidative chromogenic reagent free from interference by bilirubin used for the measurement of a biogenic substance by an enzymatic analysis, which comprises a compound or a salt thereof represented by the following formula wherein R.sup.1 and R.sup.2 independently represent a C.sub.3-4 -alkly group substituted with a sulfonic acid group or a C.sub.3-4 -hydroxyalkyl group substituted with a sulfonic acid group; and R.sup.3 and R.sup.4 independently represent a C.sub.1-4 -alkyl group, a C.sub.1-4 -alkoxy group, a substituted or non-substituted carbamoyl group, an acyl-substituted amino group, an aryl group, or a halogen atom. The reagent is stable and has excellent water solubility, and it enables high sensitive and accurate measurement because interference by bilirubin is substantially reduced or eliminated. ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.