Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives, their preparation and use

US5792764A · kind A · utility

Assignee

• Novo Nordisk A/S · DK

Inventors

• Bernard Pirotte · Liège, BE
• Philippe Lebrun · Vieusart, BE
• Pascal De Tullio · Jupille, BE
• Fabian Somers · Liège, BE
• Jacques Delarge · Dolembreux, BE
• Holger Claus Hansen · Frederikssund, DK
• Flemming E. Nielsen · Avenue Madeleine, DK
• John Bondo Hansen · Avenue Madeleine, DK

Key dates

• Filing date: Jan 17, 1997
• Grant date: Aug 11, 1998
• Expiry date: Jan 17, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P25/28
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pyrido-1,2,4-thiadiazine and pyrido-1,4-thiazine derivatives represented by the formula ##STR1## wherein A, B, D, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are defined in the description, compositions thereof and methods for preparing the compounds are described. The compounds are useful in the treatment of diseases of the central nervous system, the cardiovascular system, pulmonary system, the gastrointestinal system and the endocrinologic system.