Process for N-Boc-N-(R)-2(3-pyridyl)-2-hydroxy-ethyl)-N-2(4-aminophenyl)ethyl amine and 2-(4-aminophenyl)-N-2-(2(R)-hydroxy-2-phyridin-S-yl-ethyl)acetamide
US5792871A · kind A · utility
8Cited by
1References
2Claims
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Key dates
| Filing date | Jun 26, 1997 |
| Grant date | Aug 11, 1998 |
| Priority date | — |
| Expiry date | Jun 26, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/40
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compound 9 is prepared by a 9-step ##STR1## process in an overall yield of about 35% from 3-acetylpyridine. Compound 10 is prepared by a seven-step ##STR2## process in an overall yield of about 30% from 3-acetyl pyridine. These compounds are key intermediates in the synthesis of Compound 11, an important .beta.-3 agonist useful in the treatment of obesity and diabetes. ##STR3##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.