Androgens and anabolic agents

US5795883A · kind A · utility

Assignee

• Jenapharm GmbH · DE

Inventors

• Rolf Hesch · Lemgo, DE
• Michael Oettel · Jena, DE
• Peter Droescher · Weimar, DE
• Sigfrid Schwarz · Jena, DE
• Bernd Menzenbach · Jena, DE
• Wolfgang Romer · Jena, DE
• Gunter Kaufmann · Jena, DE
• Jens SCHRÖDER · Jena, DE

Key dates

• Filing date: Nov 6, 1995
• Grant date: Aug 18, 1998
• Expiry date: Nov 6, 2015

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J43/003
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel androgens having one or more substituents providing radical trapping properties are disclosed as useful in methods of treating androgen deficiency in man, benign prostate hypotropy and carcinoma of the prostate, osteoporosis, vascular disease-induced or ischemically-induced cerebral edemas, subarachnoid hemorrhages, ischemic shock, cerebral insult, Parkinson's disease and Alzheimer's disease. The androgen compound used for treating androgen deficiency in man has a steroid ring with an .alpha.-tocopherol group or a trolox group substituent.