Ophthalmic composition
US5795913A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 15, 1996 |
| Grant date | Aug 18, 1998 |
| Priority date | — |
| Expiry date | Mar 15, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/32
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention is directed to an ophthalmic composition in the form of a topical aqueous solution consisting essentially of PA1 an ophthalmologically active agent containing basic groups, PA1 an ion sensitive, hydrophilic polymer containing acidic groups in an amount of 0.004 to 1.5% by weight, PA1 at least one salt selected from the group of inorganic salts and buffers in a total amount of from 0.01 to 2.0% by weight, PA1 and optionally a wetting agent and a preservative, the ratio between salt and polymer being such that the solution exhibits a viscosity of less than 1000 mpas, and the pH of the solution is 4.0 to 8.0. The composition contains a sufficient amount of polymer to provide for a controlled absorption of the drug into the eye, its viscosity having been reduced to provide for better handling characteristics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.