Ligand precursors for incorporation into peptides
US5798444A · kind A · utility
0Cited by
7References
8Claims
0Family size
Inventors
Key dates
| Filing date | Sep 5, 1996 |
| Grant date | Aug 25, 1998 |
| Priority date | — |
| Expiry date | Sep 5, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02P20/55
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Compositions and methods of incorporating ligand precursors and ligands at any location within a peptide during peptide synthesis are disclosed. Derivatives of 2,4,5-triaminopentanoic acid and .gamma.-aminoglutamic acid are selectively incorporated into the peptide during solid phase or liquid phase synthesis, depending upon the choice of protecting groups. Ligand synthesis may then be completed at a later time to produce N.sub.3 S, N.sub.2 S.sub.2, and EDTA type chelating agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.