Patent · US Expired

Method and construct for producing graft tissue from an extracellular matrix

US5800537A · kind A · utility

199Cited by
23References
16Claims
0Family size

Assignee

Inventor

Key dates

Filing dateJun 6, 1995
Grant dateSep 1, 1998
Priority date
Expiry dateJun 6, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S623/915
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

Using animal tissues as starting materials, a method is described for producing extracellular matrix particulates. The invention includes an embodiment wherein the matrix particulates are applied to collagen scaffolds, which can be seeded with living cells or the particulates may alone be seeded with living cells. Further, the invention encompasses bonding the particulates to collagen foams, or collagen threads made into fabrics or to foams combined with threads. The particulates, with or without scaffolding, can be used as tissues for grafting or as model systems for research and testing. The invention also encompasses the spinning of threads on which the matrix particulates are components and the freeze drying of foams to whose surfaces the matrix particulates are attached.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.