Oral composition exhibiting enhanced uptake by dental tissue of noncationic antibacterial agents

US5800803A · kind A · utility

Assignee

• Colgate-Palmolive Company · US

Inventors

• Yelloji-Rao Mirajkar · Edison, US
• Abdul Gaffar · Somerville, US
• Stefan Stein · Saulheim, DE
• Ekkehard Jahns · Weinheim, DE
• Reinhold Dieing · Schifferstadt, DE
• Karin Sperling · Neustadt, DE

Key dates

• Filing date: Feb 10, 1997
• Grant date: Sep 1, 1998
• Expiry date: Feb 10, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K2800/594
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

An oral composition and method for use thereof, comprising in an orally acceptable vehicle, an effective antiplaque amount of a noncationic antibacterial agent, and an anionic copolymer formed from monomers of which about 40 to about 90% by weight are hydrophilic type capable of attachment to oral surfaces and about 10 to about 60% by weight are of a hydrophobic type; such oral composition being effective in increasing the uptake of the antibacterial compound to dental tissue so as to enhance the therapeutic efficacy of the administered antibacterial compound.