Implantable biocompatible immunoisolatory vehicle for delivery of selected therapeutic products
US5800828A · kind A · utility
138Cited by
35References
43Claims
0Family size
Assignee
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Key dates
| Filing date | Jan 10, 1994 |
| Grant date | Sep 1, 1998 |
| Priority date | — |
| Expiry date | Jan 10, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2510/02
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Immunoisolatory vehicles having a core and a surrounding jacket are disclosed, the core having a volume in excess of 1 .mu.l and at least about 10.sup.4 living cells capable of secreting a biologically active product or of providing a biological function to a patient, the cells dispersed in a biocompatible matrix formed of a hydrogel or an extracellular matrix component, and the external jacket being permselective, biocompatible and having a molecular weight cutoff permitting passage of molecules between the patient and the core through said jacket to provide said biological product or function.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.