Assay methods for tat cell lines
US5800986A · kind A · utility
2Cited by
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8Claims
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Assignee
Inventors
Key dates
| Filing date | Jun 1, 1995 |
| Grant date | Sep 1, 1998 |
| Priority date | — |
| Expiry date | Jun 1, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2840/44
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Assays screened for compounds that inhibit tat transactivation of the HIV (HTLV-III) LTR are taught. The assay involves tranfecting a cell line containing the tat gene by a vector containing a gene under the control of an HIV-1 LTR, adding the compound to be screened and determining the effect of the compound by looking at the effect of tat as measured by the expression of the gene under the control of the HIV LTR.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.