Detection and isolation of receptors
US5801000A · kind A · utility
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10References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 29, 1996 |
| Grant date | Sep 1, 1998 |
| Priority date | — |
| Expiry date | Feb 29, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/824
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed is a method of isolating a ligand from a sample, the method including: providing a hybrid molecule including the receptor for the ligand covalently bonded to the first member of a specific binding pair; contacting sample with the hybrid molecule to form an affinity complex between the ligand and the hybrid molecule; and isolating the affinity complex using the second member of the specific binding pair. Also disclosed is a c-kit ligand, nucleic acid encoding such a ligand, and recombinant cells containing such nucleic acid. The c-kit ligand may be used to stimulate hematopoietic cell growth.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.