Antiparasitic pyrrolobenzoxazine compounds
US5801023A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 29, 1996 |
| Grant date | Sep 1, 1998 |
| Priority date | — |
| Expiry date | Nov 29, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/66
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
This invention provides compounds of the following chemical formula or their pharmaceutically-acceptable salts: ##STR1## wherein R is hydrogen or chloro. Also, the present invention provides a process for the production of the compound of formula I, which comprises cultivating a microorganism having the identifying characteristics of Aspergillus fischeri var. thermomutatis ATCC 18618 or the like, and then isolating the compound of formula I from the fermentation broth. The pyrrolobenzoxazine compounds of formula I of this invention have broad antiparasitic activity, and thus are useful as antiparasitic agents, especially as anthelmintics.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.