Assay for agents active in proliferative disorders
US5804396A · kind A · utility
112Cited by
4References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 12, 1994 |
| Grant date | Sep 8, 1998 |
| Priority date | — |
| Expiry date | Oct 12, 2014 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2333/9121
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Method for identifying an agent for treatment of a proliferative disorder, comprising the steps of assaying a potential agent for activity in inhibition of signal transduction by a HER2/HER3 or HER2/HER4 or HER3/HER4 heterodimer. Method of screening for an agent that selectively inhibits the kinase activity of a heterodimer having one catalytically inactive component.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.