Benzoxazine derivatives, methods for obtaining same, and their use as drugs
US5804580A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1996 |
| Grant date | Sep 8, 1998 |
| Priority date | — |
| Expiry date | Jul 1, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D265/36
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds are provided corresponding to the following general formula (I): in which:--R.sub.1 and R.sub.2, independently of each other, represent an alkyl group with 1 to 3 carbon atoms, or a group of formula --CH.sub.2 --OR.sub.a, R.sub.a representing a hydrogen atom or a methyl group R.sub.x represents: an alkyl group with 1 to 3 carbon atoms, in particular a methyl group, or an --OR.sub.x1 group, R.sub.x1 representing an alkyl group with 1 to 3 carbon atoms, in particular a methoxy group, or a group of formula --CH.sub.2 --X in which X represents a halogen atom, in particular chlorine, or a group of formula (a) ##STR1## in which: R.sub.3 and R.sub.5, independently of each other, represent a hydrogen atom, or an --OH group, or an --OCH.sub.3 group, R.sub.4 represents a hydrogen atom, or an --OR.sub.b group, R.sub.b representing a hydrogen atom or a methyl group, or R.sub.4 represents a group of formula --Or.sub.c, R.sub.c representing a group of formula --CH.sub.2 --CO--C.sub.6 H.sub.4 R'. The present compounds are benzoxazine derivatives which are used for treating pathological conditions associated with the presence of free radicals, such as Alzheimer's disease, and methods are…
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.