.alpha.-Amino sulfonyl hydroxamic acids as matrix metalloproteinase inhibitors
US5804593A · kind A · utility
37Cited by
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11Claims
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Key dates
| Filing date | Oct 20, 1997 |
| Grant date | Sep 8, 1998 |
| Priority date | — |
| Expiry date | Oct 20, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/20
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of formula I or pharmaceutical acceptable salts thereof, ##STR1## wherein R.sub.1 is isopropyl, 2-methylbut-2yl, phenyl, benzyl, or 1H-indol-3ylmethyl; R.sub.2 is n-octyl, phenyl, or phenyl substituted with methoxy, fluoro, or bromo, are matrix metalloproteinase inhibitors.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.