Process for the preparation of sustained release pellets
US5807583A · kind A · utility
26Cited by
7References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 12, 1995 |
| Grant date | Sep 15, 1998 |
| Priority date | — |
| Expiry date | Jan 12, 2015 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1617
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A process for the manufacture of sustained release pellets comprising pelletizing a mixture containing the drug in finely divided form and a binder. The characteristic feature is that: PA1 (a) said binder is in particle form consisting of one or more water-insoluble wax-like binder substance(s) with a melting point above 40.degree. C., and PA1 (b) said pelletization step is performed by mechanically working said mixture, in a high shear mixer, under the input of a sufficient amount of energy for the binder to melt and pelletization to take place.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.