Patent · US Expired

Method of screening for genetic predisposition to anticholinesterase therapy

US5807671A · kind A · utility

7Cited by

0References

2Claims

0Family size

Assignee

YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. · IL

Inventors

Hermona Soreq · Nesher, IL
Haim Zakut · Savyon, IL

Key dates

Filing date	Jan 9, 1995
Grant date	Sep 15, 1998
Priority date	—
Expiry date	Jan 9, 2015

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC12Q2600/156
WIPO fieldBiotechnology
WIPO sectorChemistry

Abstract

A method of screening for a genetic predisposition to anticholinesterase exposure. The method includes the steps of obtaining a peripheral blood sample, and then analysing serum from the blood sample for BuChE levels and inhibitor-susceptibilites. The DNA of peripheral white blood cells from the blood sample is also screened for the presence of BuChE alleles thereby identifying patients who have a genetic predisposition to anticholinesterase exposure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.