Diagnostic assays and kits for RNA using RNA binary probes and a protein that is an RNA-directed RNA ligase
US5807674A · kind A · utility
24Cited by
1References
39Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Dec 12, 1994 |
| Grant date | Sep 15, 1998 |
| Priority date | — |
| Expiry date | Dec 12, 2014 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/81
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
There are provided nucleic acid hybridization assays for RNA targets using RNA binary probes and a protein that is an RNA-directed RNA ligase. Preferred assays include generation of an exponentially amplified signal. Most preferred assays include T4 DNA ligase as the RNA-directed RNA ligase. Also provided are kits for performing assays according to this invention.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.