Parenchymal hepatocyte growth factors
US5807711A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 22, 1995 |
| Grant date | Sep 15, 1998 |
| Priority date | — |
| Expiry date | Sep 22, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4753
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A novel parenchymal hepatocyte growth factor originating in a human or animal liver, having an estimated molecular weight according to nonreductive SDS-PAGE of about 63,000 to about 69,000, an estimated molecular weight according to reductive SDS-PAGE of about 32,000 to about 36,000 and an estimated molecular weight according to gel filtration of about 60 to about 70 Kd; and having an activity of effecting the growth of parenchymal hepatocyte has been obtained from the hemihepatectomized tissue. Furthermore, a gene coding for the above substance has been obtained from the mRNA of the above tissue and it has thus become possible to mass-produce the above substance.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.