Preparation of brominated paclitaxel analogues and their use as effective antitumor agents
US5807888A · kind A · utility
1Cited by
42References
14Claims
0Family size
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Inventors
Key dates
| Filing date | May 29, 1996 |
| Grant date | Sep 15, 1998 |
| Priority date | — |
| Expiry date | May 29, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D305/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Provided are novel paclitaxel analogues, namely selectively brominated stereospecific derivatives of cephalomannine and 7-epi-cephalomannine having in vivo and in vitro paclitaxel-like antitumor efficacy, methods of preparation therefor and methods for treating tumors with these compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.