Bovine pancreatic trypsin inhibitor derived inhibitors of factor VIIa-tissue factor complex
US5807980A · kind A · utility
17Cited by
6References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 1, 1993 |
| Grant date | Sep 15, 1998 |
| Priority date | — |
| Expiry date | Jul 1, 2013 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds derived from BPTI which inhibit factor VIIa-TF complex with an inhibition constant of less than 500 nM, their pharmaceutical compositions, and methods of use. Also disclosed are isolated nucleic acid segments encoding for the compounds, vectors comprising the nucleic acid segment and promoter, transformed host cells, and a method for preparing the compounds using transformed host cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.