Pyrone derivatives as protease inhibitors and antiviral agents
US5808062A · kind A · utility
12Cited by
0References
30Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 12, 1994 |
| Grant date | Sep 15, 1998 |
| Priority date | — |
| Expiry date | Oct 12, 2014 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F7/1804
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel tri- and tetrasubstituted pyrones and related structures which potently inhibit the HIV aspartyl protease blocking HIV infectivity. The pyrone derivatives are useful in the development of therapies for the treatment of bacterial and viral infections and diseases, including AIDS. The present invention is also directed to methods of synthesis of multifunctionalized pyrones and of related structures.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.