Orally administrable formulations of quinolone- or naphthyridonecarboxylic acids

US5808076A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Oliver Vetter · Burscheid, DE
• Reinhold Lohr · Bensberg, DE
• Matthias Kuhn · Monheim, DE
• Hubert Rast · Leverkusen, DE
• Martin Scheer · Wuppertal, DE
• Ernst Heinen
• Francisco Cabrera · Overland Park, US

Key dates

• Filing date: Dec 6, 1996
• Grant date: Sep 15, 1998
• Expiry date: Dec 6, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P33/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

The present invention relates to the preparation of orally administrable formulations of quinolone- or naphthyridonecarboxylic acids by mixing quinolone- or naphthyridonecarboxylic acids as such or in the form of their water-soluble salts or derivatives, preferably in the form of their aqueous salt solutions, with embonic acid as such or in the form of its water-soluble salts or derivatives, preferably in the form of its aqueous salt solutions, in the presence of an excipient, optionally in the presence of auxiliaries, when using dry mixtures in the presence of water, and optionally converting the mixture obtained into further ready-to-use forms.