Electrophoretically mediated chemical analysis
US5810985A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 9, 1995 |
| Grant date | Sep 22, 1998 |
| Priority date | — |
| Expiry date | Feb 9, 2015 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N27/44747
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Disclosed are methods of electrochemical analysis of an analyte in a sample. The methods include providing a sample comprising an analyte, and introducing the sample into a capillary tube containing electrophoretic running buffer and a reactant. According to the methods of the invention, one or both of the analyte and the reactant is electrically charged. Chemical contact between analyte and reactant induced by their relative electrophoretic mobility results in the breaking or formation of a covalent bond of one of the analyte or the reactant to produce a detectable product. The methods also include the steps of imposing along the length of the capillary tube an electric current for a time sufficient to bring into chemical contact within the tube analyte and reactant so as to allow formation of product, and detecting the product.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.