Connective tissue regeneration using human mesenchymal stem cell preparations
US5811094A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 11, 1995 |
| Grant date | Sep 22, 1998 |
| Priority date | — |
| Expiry date | Apr 11, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2533/18
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Isolated human mesenchymal stem cells, a method for isolating, purifying, and culturally expanding human mesenchymal stem cells (i.e. mesenchymal stem cells or "MSCs"), and characterization of (including by cytokine expression profiling) and uses, particularly research reagent, diagnostic and therapeutic uses for such cells. The stem cells can be culture expanded without differentiating. Monoclonal antibodies specific for human mesenchymal stem cells and the monoclonal hybridoma cell lines (ATCC nos. 10743-10745) that synthesize and secrete these monospecific antibodies, and uses of the monoclonal antibodies for diagnostic and/or therapeutic purposes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.