Formulation and use of carotenoids in treatment of cancer
US5811119A · kind A · utility
47Cited by
18References
2Claims
0Family size
Assignees
Inventors
Key dates
| Filing date | Oct 22, 1996 |
| Grant date | Sep 22, 1998 |
| Priority date | — |
| Expiry date | Oct 22, 2016 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB82Y5/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A reduced-toxicity formulation of carotenoids is disclosed which is stable in an aqueous environment. The formulation includes a carotenoid, lipid carrier particles (such as liposomes), and an intercalation promoter agent (such as a triglyceride), which causes the carotenoid to be substantially uniformly distributed with the lipid in the lipid carrier particles. The molar ratio of carotenoid to lipid is greater than about 1:10. Also disclosed is a method of inhibiting the growth of cancer cells, which comprises administering to a living subject a therapeutically effective amount of a composition as described above.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.