Patent · US Expired

Proteins with mutations to decrease N-terminal methylation

US5811264A · kind A · utility

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7Claims
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Assignee

Inventors

Key dates

Filing dateFeb 29, 1996
Grant dateSep 22, 1998
Priority date
Expiry dateFeb 29, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY02A50/30
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Mutated protein having a sequence with a non-proline amino acid replacement for a proline at amino acid position 4. The mutated protein is not methylated on its N-terminus when expressed in bacteria. The mutated protein is a mutation of a methylated protein that is at least partially methylated on its N-terminus when expressed in bacteria.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.