Method for activating prothrombin with polyethylene glycol
US5811279A · kind A · utility
3Cited by
4References
20Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 1, 1997 |
| Grant date | Sep 22, 1998 |
| Priority date | — |
| Expiry date | Aug 1, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Y304/21005
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for activating prothrombin to thrombin is presented which comprises treating an aqueous solution containing prothrombin with polyethylene glycol in the presence or absence of the calcium salt. The method enables conversion of prothrombin to thrombin in the absence of thromboplastin and allows for preparation of thrombin on an industrially large scale from easily available starting materials.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.