Process for the purification of oligomers
US5811538A · kind A · utility
3Cited by
1References
31Claims
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Key dates
| Filing date | Dec 30, 1994 |
| Grant date | Sep 22, 1998 |
| Priority date | — |
| Expiry date | Dec 30, 2014 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D15/325
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
Methods for purifying an oligomer by normal phase column chromatography on a support selected from polyhydroxyethyl aspartamide, hydrophilic silica and silica from an oligomer impurity having a different nucleoside sequence are described. These methods are based upon the different retention times of the oligomer and the impurity on the column.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.