Process for the resolution of etodolac using glucamine derivatives
US5811558A · kind A · utility
11Cited by
1References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 6, 1996 |
| Grant date | Sep 22, 1998 |
| Priority date | — |
| Expiry date | Dec 6, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C215/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The subject invention pertains to a process for the resolution of etodolac comprising the use of the resolving agent glucamine or a N-(C.sub.1-4 alkyl)-glucamine. The subject invention also concerns a process for converting a single enantiomer of etodolac into the racemate. The method comprises forming all ester of the carboxylate function of the enantiomer and treating with an acid or base.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.