Iontopheretic system for stimulation of tissue healing and regeneration
US5814094A · kind A · utility
Inventors
Key dates
| Filing date | Mar 28, 1996 |
| Grant date | Sep 29, 1998 |
| Priority date | — |
| Expiry date | Mar 28, 2016 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/31678
- WIPO fieldMedical technology
- WIPO sectorInstruments
Abstract
An iontophoretic system for promoting tissue healing processes and inducing regeneration. The system includes a device and a method, a composition, and methods for making the composition in vitro and in vivo. The system is implemented by placing a flexible, silver-containing anode in contact with the wound, placing a cathode on intact skin near the anode, and applying a wound-specific DC voltage between the anode and the cathode. Electrically-generated silver ions from the anode penetrate into the adjacent tissues and undergo a sequence of reactions leading to formation of a silver-collagen complex. This complex acts as a biological inducer to cause the formation in vivo of an adequate blastema to support regeneration.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.