Compound to mimick a naturally occurring peptide's effect
US5814316A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 5, 1994 |
| Grant date | Sep 29, 1998 |
| Priority date | — |
| Expiry date | Aug 5, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K39/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The novel compound which is the reverse amino acid sequence of a naturally occurring peptide will elicit an immune response when introduced into an organism. Antibodies raised to this reverse compound act as antagonist to the naturally occurring peptide thereby mimicking the natural peptide's physiological effect on the organism's system. Precisely, antibodies specific to reverse choleocystokinin elicit the same response in avians and mammals as naturally occurring choleocystokinin, that being an increase in satiety and a decrease in food consumption.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.