Material for buffered resorbable internal fixation devices and method for making same
US5817328A · kind A · utility
29Cited by
5References
61Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 3, 1996 |
| Grant date | Oct 6, 1998 |
| Priority date | — |
| Expiry date | Apr 3, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61F2210/0004
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A bioerodible implantable material, comprising a bioerodible polymer that produces acidic products upon hydrolytic degradation, and a buffering compound that buffers the acidic products and maintains the local pH within a desired range. The buffer compound acts to reduce the inflammatory foreign body response generated by the acidic products and reduces the sterile abscess condition that occurs at the site of the bioerodible implant materials of the prior art. Materials made according to the invention may be used for internal fixation devices (IFDs) for bone repair.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.