Process for the identification or immunoassay of polypeptide antigens
US5817468A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1996 |
| Grant date | Oct 6, 1998 |
| Priority date | — |
| Expiry date | Dec 23, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/78
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Process for the identification or assay of a particular polypeptide antigen X in which an immunological determination of the presence of said polypeptide antigen X is carried out in a sample, characterized in that the sample is treated in vitro using at least one chemical reagent reacting PA1 on an epsilon -NH.sub.2 function of a lysine residue or PA1 on a terminal alpha -NH.sub.2 function of a peptide in order to carry out the linking of said reagent to said polypeptide antigen X and in this way to obtain a modified polypeptide antigen X, (polypeptide antigen Xm), the immunological determination of the presence of said polypeptide antigen X in said sample is then carried out using at least one antibody produced by immunization against a polypeptide antigen Y identical to the polypeptide antigen Xm or to an antigenic fragment of this antigen Xm.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.